Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

BACKGROUND: Intervertebral disc (IVD) degeneration is characterized by an early decrease in cellularity of the nucleus pulposus (NP) region, and associated extracellular matrix changes, reduced hydration, and progressive degeneration. Cell-based IVD therapy has emerged as an area of great interest,...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Tang, Ruhang, Jing, Liufang, Willard, Vincent P., Wu, Chia-lung, Guilak, Farshid, Chen, Jun, Setton, Lori A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845143/
https://ncbi.nlm.nih.gov/pubmed/29523190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0797-1
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