Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice—an Aging Connection

While the refinement of existing and the development of new chemotherapeutic regimens has significantly improved cancer treatment outcomes and patient survival, chemotherapy still causes many persistent side effects. Central nervous system (CNS) toxicity is of particular concern, as cancer patients...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Kovalchuk, Anna, Ilnytskyy, Yaroslav, Rodriguez-Juarez, Rocio, Katz, Amanda, Sidransky, David, Kolb, Bryan, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845109/
https://ncbi.nlm.nih.gov/pubmed/29556248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00058
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