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Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice—an Aging Connection

While the refinement of existing and the development of new chemotherapeutic regimens has significantly improved cancer treatment outcomes and patient survival, chemotherapy still causes many persistent side effects. Central nervous system (CNS) toxicity is of particular concern, as cancer patients...

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Publicat a:Front Genet
Autors principals: Kovalchuk, Anna, Ilnytskyy, Yaroslav, Rodriguez-Juarez, Rocio, Katz, Amanda, Sidransky, David, Kolb, Bryan, Kovalchuk, Olga
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845109/
https://ncbi.nlm.nih.gov/pubmed/29556248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00058
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