Ventral Tegmental Area GABA Neurons Are Resistant to GABA(A) Receptor-Mediated Inhibition During Ethanol Withdrawal

The neural mechanisms underlying alcohol dependence are not well-understood. GABAergic neurons in the ventral tegmental area (VTA) are a relevant target for ethanol. They are inhibited by ethanol at physiologically-relevant levels in vivo and display marked hyperexcitability during withdrawal. In th...

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Pubblicato in:Front Neurosci
Autori principali: Nelson, Ashley C., Williams, Stephanie B., Pistorius, Stephanie S., Park, Hyun J., Woodward, Taylor J., Payne, Andrew J., Obray, J. Daniel, Shin, Samuel I., Mabey, Jennifer K., Steffensen, Scott C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844957/
https://ncbi.nlm.nih.gov/pubmed/29556175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00131
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