Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer’s disease

Hippocampal CA1 pyramidal neurons, a major component of the medial temporal lobe memory circuit, are selectively vulnerable during the progression of Alzheimer’s disease (AD). The cellular mechanism(s) underlying degeneration of these neurons and the relationship to cognitive performance remains lar...

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Pubblicato in:Hippocampus
Autori principali: Ginsberg, Stephen D., Malek-Ahmadi, Michael H., Alldred, Melissa J., Che, Shaoli, Elarova, Irina, Chen, Yinghua, Jeanneteau, Freddy, Kranz, Thorsten M., Chao, Moses V, Counts, Scott E., Mufson, Elliott J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844851/
https://ncbi.nlm.nih.gov/pubmed/28888073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22802
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