Cell type-specific pharmacological kinase inhibition for cancer chemoprevention

Safety is prerequisite for preventive medicine, but non-toxic agents are generally ineffective as clinical chemoprevention. Here we propose a strategy overcoming this challenge by delivering molecular-targeted agent specifically to the effector cell type to achieve sufficient potency, while circumve...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Deshmukh, Manjeet, Nakagawa, Shigeki, Higashi, Takaaki, Vincek, Adam, Venkatesh, Anu, de Galarreta, Marina Ruiz, Koh, Anna P, Goossens, Nicolas, Hirschfield, Hadassa, Bian, C Billie, Fujiwara, Naoto, Ono, Atsushi, Hoshida, Hiroki, El-Abtah, Mohamed, Ahmad, Noor B, Lujambio, Amaia, Sanchez, Roberto, Fuchs, Bryan C, Poelstra, Klaas, Prakash, Jai, Hoshida, Yujin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844817/
https://ncbi.nlm.nih.gov/pubmed/29157977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.11.004
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