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A Distinct Malignant Epithelioid Neoplasm with GLI1 Gene Rearrangements, Frequent S100 Protein Expression and Metastatic Potential: Expanding the Spectrum of Pathologic Entities with ACTB1/MALAT1/PTCH1-GLI1 Fusions

ACTB1-GLI1 fusions have been reported as the pathognomonic genetic abnormality defining an unusual subset of actin-positive, perivascular myoid tumors, known as ‘pericytoma with the t(7;12) translocation’. In addition, GLI1 oncogenic activation through a related MALAT1-GLI1 gene fusion has been rece...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Antonescu, Cristina R, Agaram, Narasimhan P, Sung, Yun-Shao, Zhang, Lei, Swanson, David, Dickson, Brendan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844813/
https://ncbi.nlm.nih.gov/pubmed/29309307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001010
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