FOXC1-Induced Non-Canonical WNT5A-MMP7 Signaling Regulates Invasiveness in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) has high rates of local recurrence and distant metastasis, partially due to its high invasiveness. The Forkhead box C1 (FOXC1) transcription factor has been shown to be specifically overexpressed in TNBC and associated with poor clinical outcome. How TNBC’s high...

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Veröffentlicht in:Oncogene
Hauptverfasser: Han, Bingchen, Zhou, Bo, Qu, Ying, Gao, Bowen, Xu, Yali, Chung, Stacey, Tanaka, Hisashi, Yang, Wei, Giuliano, Armando E., Cui, Xiaojiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844802/
https://ncbi.nlm.nih.gov/pubmed/29249801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0021-2
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