Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing

Cell fate determination during development often requires morphogen transport from producing to distant responding cells. Hedgehog (Hh) morphogens present a challenge to this concept, as all Hhs are synthesized as terminally lipidated molecules that form insoluble clusters at the surface of producin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Schürmann, Sabine, Steffes, Georg, Manikowski, Dominique, Kastl, Philipp, Malkus, Ursula, Bandari, Shyam, Ohlig, Stefanie, Ortmann, Corinna, Rebollido-Rios, Rocio, Otto, Mandy, Nüsse, Harald, Hoffmann, Daniel, Klämbt, Christian, Galic, Milos, Klingauf, Jürgen, Grobe, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844694/
https://ncbi.nlm.nih.gov/pubmed/29522397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33033
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