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Arylation of Azaarylmethylamines with Aryl Chlorides and a NiBr(2)/NIXANTPHOS-based Catalyst

A nickel-catalyzed coupling of azaarylmethylamines with aryl chlorides has been achieved. NIXANTPHOS together with low cost NiBr(2) was successfully developed and optimized to exhibit high reactivity at 2.5 mol % loading. Under optimized reaction conditions, aryl(azaaryl)methylamine products were af...

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Dettagli Bibliografici
Pubblicato in:Adv Synth Catal
Autori principali: Gao, Gui, Fu, Yue, Li, Minyan, Wang, Bo, Zheng, Bing, Hou, Shicong, Walsh, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844573/
https://ncbi.nlm.nih.gov/pubmed/29531521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700438
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