Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study

BACKGROUND: Trauma is the leading cause of death and disability in patients aged 1–46 y. Severely injured patients experience considerable blood loss and hemorrhagic shock requiring treatment with massive transfusion of red blood cells (RBCs). Preclinical and retrospective human studies in trauma pa...

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Publicado en:PLoS Med
Main Authors: Wagener, Brant M., Hu, Parker J., Oh, Joo-Yeun, Evans, Cilina A., Richter, Jillian R., Honavar, Jaideep, Brandon, Angela P., Creighton, Judy, Stephens, Shannon W., Morgan, Charity, Dull, Randal O., Marques, Marisa B., Kerby, Jeffrey D., Pittet, Jean-Francois, Patel, Rakesh P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844517/
https://ncbi.nlm.nih.gov/pubmed/29522519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002522
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