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Caloric restriction engages hepatic RNA processing mechanisms in rhesus monkeys

Caloric Restriction (CR) extends lifespan and delays the onset of age-related disorders in diverse species. Metabolic regulatory pathways have been implicated in the mechanisms of CR, but the molecular details have not been elucidated. Here we show that CR engages RNA processing of genes associated...

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Publicat a:Cell Metab
Autors principals: Rhoads, Timothy W., Burhans, Maggie S., Chen, Vincent B., Hutchins, Paul D., Rush, Matthew J. P., Clark, Josef P., Stark, Jaime L., McIlwain, Sean J., Eghbalnia, Hamid R., Pavelec, Derek M., Ong, Irene M., Denu, John M., Markley, John L., Coon, Joshua J., Colman, Ricki J., Anderson, Rozalyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844481/
https://ncbi.nlm.nih.gov/pubmed/29514073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.01.014
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