The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae

CAG/CTG trinucleotide repeats are unstable sequences that are difficult to replicate, repair, and transcribe due to their structure-forming nature. CAG repeats strongly position nucleosomes; however, little is known about the chromatin remodeling needed to prevent repeat instability. In a Saccharomy...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Koch, Melissa R., House, Nealia C. M., Cosetta, Casey M., Jong, Robyn M., Salomon, Christelle G., Joyce, Cailin E., Philips, Elliot A., Su, Xiaofeng A., Freudenreich, Catherine H.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844344/
https://ncbi.nlm.nih.gov/pubmed/29305386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300529
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