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Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans

Using combined genetic mapping, Illumina sequencing, bioinformatics analyses, and experimental validation, we identified 60 essential genes from 104 lethal mutations in two genomic regions of Caenorhabditis elegans totaling ∼14 Mb on chromosome III(mid) and chromosome V(left). Five of the 60 genes h...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Qin, Zhaozhao, Johnsen, Robert, Yu, Shicheng, Chu, Jeffrey Shih-Chieh, Baillie, David L., Chen, Nansheng
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844317/
https://ncbi.nlm.nih.gov/pubmed/29339407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300338
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