Budesonide, but not dexamethasone, blunted the response of aldosterone to renin elevation by suppressing angiotensin converting enzyme upon high-altitude exposure

INTRODUCTION: Inhaled budesonide is a novel approach to prevent acute mountain sickness (AMS). However, its mechanism is not completely understood. We aimed to investigate the effects of budesonide and dexamethasone on renin–angiotensin–aldosterone system in AMS prevention. MATERIALS AND METHODS: Da...

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Vydáno v:J Renin Angiotensin Aldosterone Syst
Hlavní autoři: Li, Hui-Jie, Zheng, Cheng-Rong, Chen, Guo-Zhu, Qin, Jun, Zhang, Ji-Hang, Yu, Jie, Zhang, En-Hao, Huang, Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843924/
https://ncbi.nlm.nih.gov/pubmed/27317302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320316653867
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