Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue

Epigenetic deregulation, such as the reduction of histone acetylation levels, is thought to be causally linked to various maladies associated with aging. Consequently, histone deacetylase inhibitors are suggested to serve as epigenetic therapy by increasing histone acetylation. However, previous wor...

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Udgivet i:Sci Rep
Main Authors: Becker, Lore, Nogueira, Melanie Schmitt, Klima, Caroline, de Angelis, Martin Hrabe, Peleg, Shahaf
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843646/
https://ncbi.nlm.nih.gov/pubmed/29520020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22674-2
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