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Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p—Me1—ROS Pathway

Cocaine abuse increases the risk of cardiovascular (CV) mortality and morbidity; however, the underlying molecular mechanisms remain elusive. By using a mouse model for cocaine abuse/use, we found that repeated cocaine injection led to increased blood pressure (BP) and aortic stiffness in mice assoc...

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Vydáno v:Hypertension
Hlavní autoři: Zhu, Wei, Wang, Huilan, Wei, Jianqin, Sartor, Gregory C, Bao, Michelle Meiqi, Pierce, Clay T, Wahlestedt, Claes R, Dykxhoorn, Derek M, Dong, Chunming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843539/
https://ncbi.nlm.nih.gov/pubmed/29483230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10213
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