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Role of Bone Morphogenetic Proteins on Cochlear Hair Cell Formation: Analyses of Noggin and Bmp2 Mutant Mice

The mammalian organ of Corti of the inner ear is a highly sophisticated sensory end organ responsible for detecting sound. Noggin is a secreted glycoprotein, which antagonizes bone morphogenetic proteins 2 and 4 (Bmp2 and Bmp4). The lack of this antagonist causes increased rows of inner and outer ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Dev Dyn
Hauptverfasser: Hwang, Chan Ho, Guo, Dayong, Harris, Marie A., Howard, Omar, Mishina, Yuji, Gan, Lin, Harris, Stephen E., Wu, Doris K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843465/
https://ncbi.nlm.nih.gov/pubmed/20063299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22200
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