CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation

Additional sex combs-like 1 (ASXL1) is a well-known tumor suppressor gene and epigenetic modifier. ASXL1 mutations are frequent in myeloid malignances; these mutations are risk factors for the development of myelodysplasia and also appear as small clones during normal aging. ASXL1 appears to act as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Wu, Zhi-Jie, Zhao, Xin, Banaszak, Lauren G., Gutierrez-Rodrigues, Fernanda, Keyvanfar, Keyvan, Gao, Shou-Guo, Raffo, Diego Quinones, Kajigaya, Sachiko, Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843401/
https://ncbi.nlm.nih.gov/pubmed/29532865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4290
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados