Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production

Fonsecaea pedrosoi (F. pedrosoi) is the most common agent of chromoblastomycosis. Transformation of this fungus from its saprophytic phase into pathogenic sclerotic cells in tissue is an essential link to the refractoriness of this infection. Experimental studies in murine models have shown that the...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Dong, Bilin, Tong, Zhongsheng, Li, Ruoyu, Chen, Sharon C.-A., Liu, Weihuang, Liu, Wei, Chen, Yao, Zhang, Xu, Duan, Yiqun, Li, Dongsheng, Chen, Liuqing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843349/
https://ncbi.nlm.nih.gov/pubmed/29481557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006237
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