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Anti-TNFα therapy in IBD alters brain activity reflecting visceral sensory function and cognitive-affective biases

BACKGROUND: In inflammatory bowel disease (IBD), immune activation with increased circulating TNF-α is linked to the intensity of gastrointestinal symptoms and depression or anxiety. A central feature of depression is cognitive biases linked to negative attributions about self, the world and the fut...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gray, Marcus A., Chao, Che-yung, Staudacher, Heidi M., Kolosky, Natasha A., Talley, Nicholas J., Holtmann, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843226/
https://ncbi.nlm.nih.gov/pubmed/29518097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193542
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