Identification of a cryptic IRF2BP2-RARA fusion in acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is characterized by fusion of RARA with PML, or rarely other gene partners. We report a patient with APL with a novel fusion between RARA and the interferon regulatory factor 2 binding protein 2 (IRF2BP2) genes. A 19-year-old woman presented with ecchymoses and epi...

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Bibliografiske detaljer
Udgivet i:J Natl Compr Canc Netw
Main Authors: Yin, C. Cameron, Jain, Nitin, Mehrotra, Meenakshi, Zhang, Jianhua, Protopopov, Alexei, Zuo, Zhuang, Pemmaraju, Naveen, DiNardo, Courtney, Hirsch-Ginsberg, Cheryl, Wang, Sa A., Medeiros, L. Jeffrey, Chin, Lynda, Patel, Keyur P., Ravandi, Farhad, Futreal, Andrew, Bueso-Ramos, Carlos E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843191/
https://ncbi.nlm.nih.gov/pubmed/25583766
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