Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1

In this study, we report the role of DNA methyltransferase 1 (DNMT1) in ultraviolet A (UVA)-induced senescence in human dermal fibroblasts (HDFs). We show that DNMT1 expression was significantly reduced during UVA-induced senescence, and this senescence could be alleviated or aggravated by the up- o...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yi, Yuxin, Xie, Hongfu, Xiao, Xiao, Wang, Ben, Du, Rui, Liu, Yingzi, Li, Zibo, Wang, Jun, Sun, Lunquan, Deng, Zhili, Li, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842848/
https://ncbi.nlm.nih.gov/pubmed/29466247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101383
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