CARMA3 is a host factor regulating the balance of inflammatory and antiviral responses against viral infection

Host response to RNA virus infection is sensed by RNA sensors such as RIG-I, which induce MAVS-mediated NF-κB and IRF3 activation to promote inflammatory and antiviral responses, respectively. Here, we found that CARMA3, a scaffold protein previously shown to mediate NF-κB activation induced by GPCR...

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Foilsithe in:Cell Rep
Main Authors: Jiang, Changying, Zhou, Zhicheng, Quan, Yanping, Zhang, Shilei, Wang, Tingting, Zhao, Xueqiang, Morrison, Clayton, Heise, Mark T., He, Wenqian, Miller, Matthew S., Lin, Xin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842788/
https://ncbi.nlm.nih.gov/pubmed/26947079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.031
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