Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice

Intercellular transfer of microRNAs can mediate communication between critical effector cells. We hypothesized that transfer of neutrophil-derived microRNAs to pulmonary epithelial cells could alter mucosal gene expression during acute lung injury. Pulmonary-epithelial microRNA profiling during cocu...

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Publicado no:Sci Transl Med
Main Authors: Neudecker, Viola, Brodsky, Kelley S., Clambey, Eric T., Schmidt, Eric P., Packard, Thomas A., Davenport, Bennett, Standiford, Theodore J., Weng, Tingting, Fletcher, Ashley A., Barthel, Lea, Masterson, Joanne C., Furuta, Glenn T., Cai, Chunyan, Blackburn, Michael R., Ginde, Adit A., Graner, Michael W., Janssen, William J., Zemans, Rachel L., Evans, Christopher M., Burnham, Ellen L., Homann, Dirk, Moss, Marc, Kreth, Simone, Zacharowski, Kai, Henson, Peter M., Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842431/
https://ncbi.nlm.nih.gov/pubmed/28931657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah5360
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