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Sequential addition of reprogramming factors improves efficiency

Addition of a specific set of transcription factors reprograms somatic cell nuclei to a pluripotent state. Sequential addition of these factors, rather than the simultaneous exposure used in standard protocols, improves reprogramming efficiency. This sequential method favors a transition through a s...

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Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Gaeta, X, Xie, Y, Lowry, WE
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842428/
https://ncbi.nlm.nih.gov/pubmed/23817236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2800
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