Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids

Repository corticotrophin injection (RCI, H.P Acthar(®) gel) has been approved for use in the management of multiple autoimmune and inflammatory diseases for more than a half‐century, but its mechanism of action is not well understood. We used RNA‐Seq methods to define RCI‐regulated mRNAs in culture...

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Publicat a:Clin Exp Immunol
Autors principals: Benko, A. L., McAloose, C. A., Becker, P. M., Wright, D., Sunyer, T., Kawasawa, Y. I., Olsen, N. J., Kovacs, W. J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842415/
https://ncbi.nlm.nih.gov/pubmed/29205315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13089
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