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Why target the tumor stroma in melanoma?
Melanoma metastasis is fatal. Melanoma cells are often characterized by an activated extracellular signal–regulated kinase (ERK) pathway downstream of mutations in BRAF. Therapies targeting these BRAF mutations are useful for a while; however, patients ultimately develop resistance to these therapie...
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| 出版年: | J Cell Commun Signal |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842182/ https://ncbi.nlm.nih.gov/pubmed/29110248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0419-1 |
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