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Protein kinase C is a calcium sensor for presynaptic short-term plasticity
In presynaptic boutons, calcium (Ca(2+)) triggers both neurotransmitter release and short-term synaptic plasticity. Whereas synaptotagmins are known to mediate vesicle fusion through binding of high local Ca(2+) to their C2 domains, the proteins that sense smaller global Ca(2+) increases to produce...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841930/ https://ncbi.nlm.nih.gov/pubmed/25097249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03011 |
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