Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

Background: We investigated causal effect of completed growth, measured by adult height, on coronary heart disease (CHD), stroke and cardiovascular traits, using instrumental variable (IV) Mendelian randomization meta-analysis. Methods: We developed an allele score based on 69 single nucleotide poly...

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Detalhes bibliográficos
Publicado no:Int J Epidemiol
Main Authors: Nüesch, Eveline, Dale, Caroline, Palmer, Tom M, White, Jon, Keating, Brendan J, van Iperen, Erik PA, Goel, Anuj, Padmanabhan, Sandosh, Asselbergs, Folkert W, Verschuren, WM, Wijmenga, C, Van der Schouw, YT, Onland-Moret, NC, Lange, Leslie A, Hovingh, GK, Sivapalaratnam, Suthesh, Morris, Richard W, Whincup, Peter H, Wannamethe, Goya S, Gaunt, Tom R, Ebrahim, Shah, Steel, Laura, Nair, Nikhil, Reiner, Alexander P, Kooperberg, Charles, Wilson, James F, Bolton, Jennifer L, McLachlan, Stela, Price, Jacqueline F, Strachan, Mark WJ, Robertson, Christine M, Kleber, Marcus E, Delgado, Graciela, März, Winfried, Melander, Olle, Dominiczak, Anna F, Farrall, Martin, Watkins, Hugh, Leusink, Maarten, Maitland-van der Zee, Anke H, de Groot, Mark CH, Dudbridge, Frank, Hingorani, Aroon, Ben-Shlomo, Yoav, Lawlor, Debbie A, Amuzu, A, Caufield, M, Cavadino, A, Cooper, J, Davies, TL, Drenos, F, Engmann, J, Finan, C, Giambartolomei, C, Hardy, R, Humphries, SE, Hypponen, E, Kivimaki, M, Kuh, D, Kumari, M, Ong, K, Plagnol, V, Power, C, Richards, M, Shah, S, Shah, T, Sofat, R, Talmud, PJ, Wareham, N, Warren, H, Whittaker, JC, Wong, A, Zabaneh, D, Davey Smith, George, Wells, Jonathan C, Leon, David A, Holmes, Michael V, Casas, Juan P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Mendelian Randomisation and Instrumental Variable Analysis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841831/
https://ncbi.nlm.nih.gov/pubmed/25979724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv074
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