Deep sequencing of HBV pre-S region reveals high heterogeneity of HBV genotypes and associations of word pattern frequencies with HCC

Hepatitis B virus (HBV) infection is a common problem in the world, especially in China. More than 60–80% of hepatocellular carcinoma (HCC) cases can be attributed to HBV infection in high HBV prevalent regions. Although traditional Sanger sequencing has been extensively used to investigate HBV sequ...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Bai, Xin, Jia, Jian-an, Fang, Meng, Chen, Shipeng, Liang, Xiaotao, Zhu, Shanfeng, Zhang, Shuqin, Feng, Jianfeng, Sun, Fengzhu, Gao, Chunfang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841821/
https://ncbi.nlm.nih.gov/pubmed/29474353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007206
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