Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease

Induced pluripotent stem cells (iPSCs) have recapitulated several aspects of Parkinson’s disease (PD), but most iPSCs are derived from familial cases, which account for only about 15% of patients. Thus, while the emphasis has justifiably been on using iPSCs to model rare familial cases, models for t...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Marrone, Lara, Bus, Christine, Schöndorf, David, Fitzgerald, Julia Catherine, Kübler, Manuela, Schmid, Benjamin, Reinhardt, Peter, Reinhardt, Lydia, Deleidi, Michela, Levin, Tanya, Meixner, Andrea, Klink, Barbara, Glatza, Michael, Gloeckner, Christian Johannes, Gasser, Thomas, Sterneckert, Jared
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841660/
https://ncbi.nlm.nih.gov/pubmed/29513666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192497
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