Hypoxia-Induced Matrix Metalloproteinase-13 Expression in Exosomes from Nasopharyngeal Carcinoma Enhances Metastases

Exosomes are nano-vesicles secreted by tumor cells. Exosomes can transfer complex biological information and induce a diverse signaling response in a wide array of pathological conditions, such as hypoxia. Hypoxia is associated with aggressive phenotypes and poor outcomes in nasopharyngeal carcinoma...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Shan, Ying, You, Bo, Shi, Si, Shi, Wei, Zhang, Zhenxin, Zhang, Qicheng, Gu, Miao, Chen, Jing, Bao, Lili, Liu, Dong, You, Yiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841433/
https://ncbi.nlm.nih.gov/pubmed/29515112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0425-0
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