Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma

BACKGROUND: Glioblastoma multiforme (GBM) is the most malignant primary tumor of the central nervous system and is associated with a very poor prognosis. No further improvements in outcomes have been reported since radiotherapy-temozolomide therapy was introduced. Therefore, developing new agents to...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Wang, Rong, Deng, Danni, Shao, Naiyuan, Xu, Yuan, Xue, Lian, Peng, Ya, Liu, Yatian, Zhi, Feng
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841348/
https://ncbi.nlm.nih.gov/pubmed/29535541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155275
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