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Detailed analysis of clonal evolution and cytogenetic evolution patterns in patients with myelodysplastic syndromes (MDS) and related myeloid disorders

Clonal cytogenetic evolution (CE) (i.e., acquisition of new chromosomal aberrations over time) is relevant for the progression of myelodysplastic syndromes (MDS). We performed detailed analysis of CE in 729 patients with MDS and related disorders. Patients with CE showed shorter survival (median OS...

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Détails bibliographiques
Publié dans:Blood Cancer J
Auteurs principaux: Schanz, Julie, Cevik, Naciye, Fonatsch, Christa, Braulke, Friederike, Shirneshan, Katayoon, Bacher, Ulrike, Haase, Detlef
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841340/
https://ncbi.nlm.nih.gov/pubmed/29515104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-018-0061-z
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