Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging

Focused ultrasound (FUS) exposure with microbubbles can transiently open the blood-brain barrier (BBB) to deliver therapeutic molecules into CNS tissues. However, delivered molecular distribution/concentration at the target need to be controlled. Dynamic Contrast-Enhanced Magnetic-Resonance Imaging...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chai, Wen-Yen, Chu, Po-Chun, Tsai, Chih-Hung, Lin, Chung-Yin, Yang, Hung-Wei, Lai, Hsin-Yi, Liu, Hao-Li
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841286/
https://ncbi.nlm.nih.gov/pubmed/29515222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22571-8
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