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A mini-library system to investigate non-essential residues of lipid-phosphatidylserine (PS) binding peptide–peptoid hybrid PPS1

We recently identified a peptide–peptoid hybrid, PPS1, which specifically recognized lipid-phosphatidylserine (PS). PPS1 consists of distinct positively charged and hydrophobic residue-containing regions. The PPS1 monomer was inactive, but the dimeric form, PPS1D1, displayed strong cytotoxicity to l...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Shukla, Satya Prakash, Udugamasooriya, D. Gomika
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841255/
https://ncbi.nlm.nih.gov/pubmed/29527284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00372b
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