Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients

Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) in cell culture and protection against lethal challenge in mi...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Scheuch, Gerhard, Canisius, Sebastian, Nocker, Karlheinz, Hofmann, Thomas, Naumann, Rolf, Pleschka, Stephan, Ludwig, Stephan, Welte, Tobias, Planz, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841227/
https://ncbi.nlm.nih.gov/pubmed/29511170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0023-3
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