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Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients

BACKGROUND: Multiple sclerosis (MS) is characterized by increased activation of peripheral blood mononuclear cells (PBMCs), linked to perturbations in the phosphorylation of signaling proteins. METHODS: We developed a phosphoflow cytometry protocol to assess the levels of 11 phosphorylated nuclear p...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Canto, Ester, Isobe, Noriko, Didonna, Alessandro, Hauser, Stephen L., Oksenberg, Jorge R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840794/
https://ncbi.nlm.nih.gov/pubmed/29514694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1105-9
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