Early alpha-lipoic acid therapy protects from degeneration of the inner retinal layers and vision loss in an experimental autoimmune encephalomyelitis-optic neuritis model

BACKGROUND: In multiple sclerosis (MS), neurodegeneration is the main reason for chronic disability. Alpha-lipoic acid (LA) is a naturally occurring antioxidant which has recently been demonstrated to reduce the rate of brain atrophy in progressive MS. However, it remains uncertain if it is also ben...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Dietrich, Michael, Helling, Niklas, Hilla, Alexander, Heskamp, Annemarie, Issberner, Andrea, Hildebrandt, Thomas, Kohne, Zippora, Küry, Patrick, Berndt, Carsten, Aktas, Orhan, Fischer, Dietmar, Hartung, Hans-Peter, Albrecht, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840773/
https://ncbi.nlm.nih.gov/pubmed/29514678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1111-y
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