Dual IRE1 RNase functions dictate glioblastoma development

Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer development. This concept is valid in glioblastoma multiform (G...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Lhomond, Stéphanie, Avril, Tony, Dejeans, Nicolas, Voutetakis, Konstantinos, Doultsinos, Dimitrios, McMahon, Mari, Pineau, Raphaël, Obacz, Joanna, Papadodima, Olga, Jouan, Florence, Bourien, Heloise, Logotheti, Marianthi, Jégou, Gwénaële, Pallares‐Lupon, Néstor, Schmit, Kathleen, Le Reste, Pierre‐Jean, Etcheverry, Amandine, Mosser, Jean, Barroso, Kim, Vauléon, Elodie, Maurel, Marion, Samali, Afshin, Patterson, John B, Pluquet, Olivier, Hetz, Claudio, Quillien, Véronique, Chatziioannou, Aristotelis, Chevet, Eric
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840541/
https://ncbi.nlm.nih.gov/pubmed/29311133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707929
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