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Bidirectional Regulation of AdpA(ch) in Controlling the Expression of scnRI and scnRII in the Natamycin Biosynthesis of Streptomyces chattanoogensis L10

AdpA, an AraC/XylS family protein, had been proved as a key regulator for secondary metabolism and morphological differentiation in Streptomyces griseus. Here, we identify AdpA(ch), an ortholog of AdpA, as a “higher level” pleiotropic regulator of natamycin biosynthesis with bidirectional regulatory...

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Publié dans:Front Microbiol
Auteurs principaux: Yu, Pin, Bu, Qing-Ting, Tang, Yi-Li, Mao, Xu-Ming, Li, Yong-Quan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840217/
https://ncbi.nlm.nih.gov/pubmed/29551998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00316
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