Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma

PURPOSE: Adoptive cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) for metastatic melanoma can be highly effective, but attrition due to progression before TIL administration (32% in prior institutional experience) remains a limitation. We hypothesized that combining ACT with cytotoxic...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Mullinax, John E., Hall, MacLean, Prabhakaran, Sangeetha, Weber, Jeffrey, Khushalani, Nikhil, Eroglu, Zeynep, Brohl, Andrew S., Markowitz, Joseph, Royster, Erica, Richards, Allison, Stark, Valerie, Zager, Jonathan S., Kelley, Linda, Cox, Cheryl, Sondak, Vernon K., Mulé, James J., Pilon-Thomas, Shari, Sarnaik, Amod A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840208/
https://ncbi.nlm.nih.gov/pubmed/29552542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00044
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