Response to crizotinib in a non-small-cell lung cancer patient harboring an EML4-ALK fusion with an atypical LTBP1 insertion

Fusion of the anaplastic lymphoma receptor tyrosine kinase gene (ALK) with the echinoderm microtubule-associated protein 4 gene (EML4) is the second most common actionable alteration in non-small-cell lung cancer, with a frequency of 5%. Here, we present a case of an EML4-ALK-positive patient with a...

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Библиографические подробности
Опубликовано в: :Onco Targets Ther
Главные авторы: Aguado, Cristina, Gil, Maria-de-los-Llanos, Yeste, Zaira, Giménez-Capitán, Ana, Teixidó, Cristina, Karachaliou, Niki, Viteri, Santiago, Rosell, Rafael, Molina-Vila, Miguel A
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
Предметы:
Case Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840185/
https://ncbi.nlm.nih.gov/pubmed/29535536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S148363
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