Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis

T cells reacting to self-components can promote tissue damage when escaping tolerogenic control mechanisms which may result in autoimmune disease. The current treatments for these disorders are not antigen (Ag) specific and can compromise host immunity through chronic suppression. We have previously...

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Vydáno v:Front Immunol
Hlavní autoři: LaMothe, Robert A., Kolte, Pallavi N., Vo, Trinh, Ferrari, Joseph D., Gelsinger, Tracy C., Wong, Jodie, Chan, Victor T., Ahmed, Sinthia, Srinivasan, Aditi, Deitemeyer, Patrick, Maldonado, Roberto A., Kishimoto, Takashi K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840162/
https://ncbi.nlm.nih.gov/pubmed/29552007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00281
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