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Divergent requirement of T-box transcription factors in effector and memory NK cells

The T-box transcription factors T-bet and Eomesodermin (Eomes) instruct discrete stages in natural killer (NK) cell development. However, their role in the immune response of mature NK cells against pathogens remains unexplored. We used an inducible deletion system to elucidate the cell-intrinsic ro...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Madera, Sharline, Geary, Clair D., Lau, Colleen M., Pikovskaya, Olga, Reiner, Steven L., Sun, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840019/
https://ncbi.nlm.nih.gov/pubmed/29440505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700416
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