Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation

BACKGROUND: The long-term probability of developing atrial fibrillation (AF) considering genetic predisposition and clinical risk factor burden is unknown. METHODS: We estimated lifetime risk of AF in individuals from the community-based Framingham Heart Study. Polygenic risk for AF was derived usin...

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Bibliographic Details
Published in:Circulation
Main Authors: Weng, Lu-Chen, Preis, Sarah R., Hulme, Olivia L., Larson, Martin G., Choi, Seung Hoan, Wang, Biqi, Trinquart, Ludovic, McManus, David D., Staerk, Laila, Lin, Honghuang, Lunetta, Kathryn L., Ellinor, Patrick T., Benjamin, Emelia J., Lubitz, Steven A.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840011/
https://ncbi.nlm.nih.gov/pubmed/29129827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.031431
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