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Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α

BACKGROUND: Curcumin has been used as an alternative medicine for the treatment of infantile hemangiomas (IHs); however, the mechanism underlying the effectiveness of curcumin in IHs remains largely unclear. METHODS: In this study, we isolated primary human hemangioma endothelial cells (HemECs) from...

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Bibliographische Detailangaben
Veröffentlicht in:Medicine (Baltimore)
Hauptverfasser: Lou, Suhui, Wang, Yanfang, Yu, Zujiang, Guan, Kelei, Kan, Quancheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839849/
https://ncbi.nlm.nih.gov/pubmed/29443732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000009562
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