Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Exosomes are small endosome-derived extracellular vesicles implicated in cell–cell communication and are secreted by living cells when multivesicular bodies (MVBs) fuse with the plasma membrane (PM). Current techniques to study exosome physiology are based on isolation procedures after secretion, pr...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Verweij, Frederik Johannes, Bebelman, Maarten P., Jimenez, Connie R., Garcia-Vallejo, Juan J., Janssen, Hans, Neefjes, Jacques, Knol, Jaco C., de Goeij-de Haas, Richard, Piersma, Sander R., Baglio, S. Rubina, Verhage, Matthijs, Middeldorp, Jaap M., Zomer, Anoek, van Rheenen, Jacco, Coppolino, Marc G., Hurbain, Ilse, Raposo, Graça, Smit, Martine J., Toonen, Ruud F.G., van Niel, Guillaume, Pegtel, D. Michiel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839777/
https://ncbi.nlm.nih.gov/pubmed/29339438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703206
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