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The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression

The role of formins in microtubules is not well understood. In this study, we have investigated the mechanism by which INF2, a formin mutated in degenerative renal and neurological hereditary disorders, controls microtubule acetylation. We found that silencing of INF2 in epithelial RPE-1 cells produ...

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Publicat a:J Cell Biol
Autors principals: Fernández-Barrera, Jaime, Bernabé-Rubio, Miguel, Casares-Arias, Javier, Rangel, Laura, Fernández-Martín, Laura, Correas, Isabel, Alonso, Miguel A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839776/
https://ncbi.nlm.nih.gov/pubmed/29321169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702157
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