Enhanced Hypothalamic NMDA Receptor Activity Contributes to Hyperactivity of HPA Axis in Chronic Stress in Male Rats

Chronic stress stimulates corticotrophin-releasing hormone (CRH)–expressing neurons in the paraventricular nucleus (PVN) of the hypothalamus and leads to hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, but the mechanisms underlying this action are unknown. Because chronic stress enhances N-...

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發表在:Endocrinology
Main Authors: Zhou, Jing-Jing, Gao, Yonggang, Zhang, Xiangjian, Kosten, Therese A., Li, De-Pei
格式: Artigo
語言:Inglês
出版: Endocrine Society 2018
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839733/
https://ncbi.nlm.nih.gov/pubmed/29390057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-03176
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